Metro by metro
The leading pharmacy chains in every Kentucky metro area
Tracked pharmacy chains ranked by consumer spend in each metro area, Q4 2025–Q3 2026. Walgreens leads in 5 metro areas, CVS Pharmacy in 3 metro areas. Against their share in Kentucky as a whole, Walgreens stands out in 4 metro areas, CVS Pharmacy in 4 metro areas.
By tracked consumer spend, Q4 2025–Q3 2026
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Walgreens
Relative #1 in 4 metro areas
Louisville, KY (KY part) 1.3× · Cincinnati, OH-KY-IN (KY part) 1.3× · Huntington-Ashland, WV-KY-OH (KY part) 0.4× · Elizabethtown, KY 1.2×
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CVS Pharmacy
Relative #1 in 4 metro areas
Lexington-Fayette, KY 1.6× · Bowling Green, KY 1× · Owensboro, KY 1.9× · Paducah, KY-IL (KY part) 2×
Not enough tracked stores: Clarksville, TN-KY (KY part)
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Walgreens
#1 in 5 metro areas
Louisville, KY (KY part) · Lexington-Fayette, KY · Cincinnati, OH-KY-IN (KY part) · Bowling Green, KY · Elizabethtown, KY
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CVS Pharmacy
#1 in 3 metro areas
Huntington-Ashland, WV-KY-OH (KY part) · Owensboro, KY · Paducah, KY-IL (KY part)
Not enough tracked stores: Clarksville, TN-KY (KY part)
A metro area shows a ranking once it has at least 2 tracked pharmacy chains and 10 tracked stores. Relative to Kentucky compares a chain's share of the metro area's spend with its share in Kentucky as a whole. It ranks the 7 biggest chains in Kentucky and the chains that lead a metro area by spend, wherever a chain has at least 5% of the metro area's spend and 3 stores there. Metro areas are the Census Bureau's metropolitan statistical areas; the rest of Kentucky is light gray. A metro area crossing the state line counts only its stores in Kentucky. Colors match the store map; other tracked chains are gray.
Growth ranking
Fastest-growing tracked pharmacy chains
Ranked by year-over-year growth of share of tracked local spend. Arrows show movement in the rankings since last year. Each dot in the chart is one tracked chain: bigger market position to the right, faster growth higher up, more tracked stores in a bigger dot. Colors match the store map below. Hometown Pharmacy and Thompson Drug sit in the high-growth half.
| Rank | Chain | Rank movement | YoY growth |
|---|---|---|---|
| 1 | Hometown Pharmacy | ▲2 | +14.1% |
| 2 | Thompson Drug | ▲1 | +13.4% |
| 3 | Clinic Pharmacy | ▲1 | +8.2% |
| 4 | Genoa Healthcare | ▲1 | +1.0% |
| 5 | Midway Pharmacy | - | +0.5% |
| 6 | CVS Pharmacy | - | +0.1% |
| 7 | Ruwe Family Pharmacy | ▲1 | -2.5% |
| 8 | Walgreens | - | -2.6% |
| 9 | Total Pharmacy Care | - | -6.3% |
| 10 | Poole's Pharmacy Care | ▼1 | -9.4% |
| 11 | Medica Pharmacy | ▼1 | -13.1% |
| 12 | Medicine Shoppe | ▲1 | -14.8% |
| 13 | Medical Arts Pharmacy | ▼1 | -44.6% |
| 14 | Total Care Pharmacy | ▼4 | -76.5% |
- Walgreens
- CVS Pharmacy
- Walmart Pharmacy
- Sheldon's Express Pharmacy
- Lexington Compounding Pharmacy
- Rx Alternatives
- Compound Care Pharmacy
- Other tracked chains
Store footprint
Store map
604 tracked store locations in Kentucky. The 7 largest tracked chains are highlighted. The top 5 chains by store count run 265 of the 604 stores (44%); 285 of the 311 tracked chains have a single store here. 10% of the tracked health & beauty stores here are pharmacies, against 9% across the United States.
- Walgreens (164)
- CVS Pharmacy (85)
- Walmart Pharmacy (1)
- Sheldon's Express Pharmacy (2)
- Lexington Compounding Pharmacy (1)
- Rx Alternatives (1)
- Compound Care Pharmacy (1)
- Other tracked chains
Top tracked chains by store count
- 1 Walgreens 164
- 2 CVS Pharmacy 85
- 3 Thompson Drug 6
- 4 Medicine Shoppe 6
- 5 Poole's Pharmacy Care 4
- 6 Hometown Pharmacy 4
- 7 Total Care Pharmacy 4
- 8 Midway Pharmacy 3
- 9 Medical Arts Pharmacy 3
- 10 Genoa Healthcare 3
- 11 Total Pharmacy Care 3
- 12 Medica Pharmacy 3
- 13 Ruwe Family Pharmacy 3
- 14 Clinic Pharmacy 3
- 15 Med-Save 3
- 16 Ely Drugs 2
- 17 Apothecare Pharmacy 2
- 18 King Drug and Home Care 2
- 19 Grace Health 2
- 20 Audubon Pharmacy 2
- 21 Eastridge-Phelps Pharmacy 2
- 22 Grant County Drugs 2
- 23 Medicine Cabinet Pharmacy 2
- 24 Family Discount Drugs 2
- 25 Sheldon's Express Pharmacy 2
- 26 ARH Prescription Division 1
- 27 Morton's Discount Drug 1
- 28 Knight's Pharmacy 1
- 29 Silvers Hometown Pharmacy 1
- 30 Davis Drugs 1
- 31 KB Pharmacy 1
- 32 Commonwealth Pharmacy 1
- 33 Adelaide Apothecary LLC 1
- 34 Louisa Drug Store 1
- 35 Thrifty Pharmacy 1
- 36 Whitaker Pharmacy 1
- 37 Grant County Drugs North 1
- 38 Horton Brothers & Brown Compounding Pharmacy 1
- 39 Rice Pharmacy 1
- 40 Clays Pharmacy 1
- 41 Nancy Pharmacy 1
- 42 Whitley's Pharmacy 1
- 43 Warnell Family Pharmacy and Soda Shoppe 1
- 44 Wagner's Pharmacy 1
- 45 Optimum Wellness Center 1
- 46 McConnell Health Mart Pharmacy 1
- 47 Corbin Pharmacy 1
- 48 Hubbard and Curry Med Save 1
- 49 Cumberland Drug Co. 1
- 50 Value-Med Pharmacy 1
More trends